How To Determine If You Have My C3 Mutation (rs147859257)
The two cheapest tests that query the single nucleotide polymorphism (SNP) in Complement Component 3 that we’re interested in are AncestryDNA (regularly $99, but you can find occasional sales as low as $59) and 23andMe ($199 for health & ancestry, $99 for ancestry alone, often on sale for less). As of February 2018, FamilyTreeDNA does not query this SNP, though this is also a good company, especially for mitochondrial and Y-DNA sequencing. Ancestry queries 668,942 SNPs, and 23andMe queries 638,463 SNPs (based on our test results). Both will allow you to connect with DNA relatives, but Ancestry is more sophisticated and has a broad network linked to genealogical information if this is your primary interest. Though Ancestry will provide you with more specific information on your ancestral heritage, it will not specify health or trait information like 23andMe’s health version, which is limited but updates with new information from time to time. However, there are many programs online that can extract much more health and trait information for a minor cost ($25+, to be discussed in a later post) if you prefer the cheaper price and more specific ancestral information of AncestryDNA or the ancestry only version of 23andMe. They are both good companies, so it’s up to you.